After 3 games (2 vs User and 1 vs Computer after a late disconnect) I'm of the following opinion on the changes:
Offense is way too easy. Score and yards are way up and I think it is a direct result of the CBs not responding as quick and they used to and not punishing for bad decisions. Offenses are getting away with a lot of throws that they shouldn't get away with. The CPU picks are basically non-existent as they almost always drop balls right in their hands. User picks seem to be about right. If you're there and make the right play you pick it off 50-66% of the time, drop it 20-30% of the time and blow it completely the rest of the time. I am a firm believer that at least 75% of the INTs thrown last season were a direct result of not reading the D properly and throwing to covered guys, 15-20% were because of great User plays, and 5-10% were just crazy plays by the CPU that shouldn't have been made. Granted, I'm fortunate enough to have one of the better QBs in the game, but after starting off throwing a ton of picks, I hardly threw any the second half of the season and playoffs just by practicing, making better decisions, reading Ds and throwing the ball away or taking a sack. I would say I was averaging 1 INT or less the second half of the season last year.
To me, I would much rather see high INT numbers than see 500-600 yards per game and scores regularly exceeding 40 and even 50 points. I'm not sure exactly what sliders there are available and I'm away from the Box to look them up, but if there were a slider that increases the number of passes CBs break up I would increase that significantly and if there was one for their catching I would increase that slightly.
As far as vs. CPU games go, they are still pretty bad but are improved. They made a few nice plays in my game, they were few and far between and they couldn't stop me at all. However, they did make some ridiculous interceptions with LBs jumping off imaginary trampolines and using their go go gadget arms to pick off a couple passes.